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ABOUT OTEZLA

Otezla is a prescription medicine approved for the treatment of patients with moderate to severe plaque psoriasis for whom phototherapy or systemic therapy is appropriate.

Otezla is also a prescription medicine approved for the treatment of adult patients with active psoriatic arthritis.

Otezla is a convenient pill. It’s different. Otezla is not an injection, not a cream, not a biologic, and not a shampoo. The Prescribing Information for Otezla has no requirement for initial or ongoing lab monitoring.

PATIENT SUPPORT

Treatment for psoriatic disease

When you live with psoriatic disease, it’s important to surround yourself with a support system. SupportPlus™; is an exclusive program for people taking Otezla® (apremilast), as well as those looking for more information on treatment. It’s designed to support you every step of the way. It offers support throughout your journey, including information about Otezla, and more.


For more information about Otezla, please visit Otezla Support Plus;
or call 1-844-4OTEZLA (1-844-468-3952), 8AM–8PM ET, Monday–Friday.

A PILL THAT TREATS PLAQUE PSORIASIS OR PSORIATIC ARTHRITIS DIFFERENTLY.

APPROVED USES

Otezla® (apremilast) is a prescription medicine approved for the treatment of patients with moderate to severe plaque psoriasis for whom phototherapy or systemic therapy is appropriate.

Otezla is a prescription medicine approved for the treatment of adult patients with active psoriatic arthritis.

IMPORTANT SAFETY INFORMATION

You must not take Otezla® (apremilast) if you are allergic to apremilast or to any of the ingredients in Otezla.

Otezla is associated with an increase in adverse reactions of depression. In clinical studies, some patients reported depression and suicidal behavior while taking Otezla. Some patients stopped taking Otezla due to depression. Before starting Otezla, tell your doctor if you have had feelings of depression, suicidal thoughts, or suicidal behavior. Be sure to tell your doctor if any of these symptoms or other mood changes develop or worsen during treatment with Otezla.

Some patients taking Otezla lost body weight. Your doctor should monitor your weight regularly. If unexplained or significant weight loss occurs, your doctor will decide if you should continue taking Otezla.

Some medicines may make Otezla less effective, and should not be taken with Otezla. Tell your doctor about all the medicines you take, including prescription and nonprescription medicines.

Side effects of Otezla in psoriasis clinical studies were diarrhea, nausea, upper respiratory tract infection, tension headache, and headache.

Side effects of Otezla in psoriatic arthritis clinical studies were diarrhea, nausea, and headache.

These are not all the possible side effects with Otezla. Ask your doctor about other potential side effects. Tell your doctor about any side effect that bothers you or does not go away.

Tell your doctor if you are pregnant, planning to become pregnant, or planning to breastfeed. Otezla has not been studied in pregnant women or in women who are breastfeeding.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-332-1088.

Please click here for Full Prescribing Information.

Otezla® is a registered trademark of Celgene Corporation.

© 2017 Celgene Corporation 06/17
USII-APR170021

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