FOR U.S. AUDIENCES ONLY

ABOUT PSORIATIC ARTHRITIS (PsA)

Over 1 million people in the United States live with psoriatic arthritis. Psoriatic arthritis, also known as PsA, is a chronic inflammatory condition that includes swelling, pain, and joint tenderness. Up to 30% of people with psoriasis eventually develop PsA. It may impact patients in their daily activities such as walking or climbing stairs. While there is no cure for PsA, its symptoms may be managed.

PsA SYMPTOMS SPOTLIGHT

Symptoms of Psoriatic Arthritis Pain and swelling
in the joints
Symptoms of Psoriatic Arthritis Swollen fingers
and toes
Symptoms of Psoriatic Arthritis Inflammation
and pain where
ligaments and
tendons attach
to bone
Psoriatic Arthritis Diagnosis

A FOCUS ON DIAGNOSIS

Psoriatic Arthritis Diagnosis

There are no tests to confirm a PsA diagnosis. However, a doctor, such as a rheumatologist, may do a physical exam, looking for swelling and inflammation of the joints, looking for abnormalities in nails, and collecting information from the patient about where their pain exists. Prior history of psoriasis may also be considered when making a diagnosis.

Diagnosis is sometimes complicated by the fact that some of the symptoms of PsA are similar to those of rheumatoid arthritis, gout, and reactive arthritis. Talk to your doctor if you think you may be experiencing PsA symptoms.

HOW TO MANAGE PsA

Create a disease
management plan
with your doctor
Ask your doctor
if you should make
changes in your daily
activities
Ask your doctor about
possible changes to
your treatment

PATIENT RESOURCES

A PILL THAT TREATS PLAQUE PSORIASIS OR PSORIATIC ARTHRITIS DIFFERENTLY.

APPROVED USES

Otezla® (apremilast) is a prescription medicine approved for the treatment of patients with moderate to severe plaque psoriasis for whom phototherapy or systemic therapy is appropriate.

Otezla is a prescription medicine approved for the treatment of adult patients with active psoriatic arthritis.

IMPORTANT SAFETY INFORMATION

You must not take Otezla® (apremilast) if you are allergic to apremilast or to any of the ingredients in Otezla.

Otezla is associated with an increase in adverse reactions of depression. In clinical studies, some patients reported depression and suicidal behavior while taking Otezla. Some patients stopped taking Otezla due to depression. Before starting Otezla, tell your doctor if you have had feelings of depression, suicidal thoughts, or suicidal behavior. Be sure to tell your doctor if any of these symptoms or other mood changes develop or worsen during treatment with Otezla.

Some patients taking Otezla lost body weight. Your doctor should monitor your weight regularly. If unexplained or significant weight loss occurs, your doctor will decide if you should continue taking Otezla.

Some medicines may make Otezla less effective, and should not be taken with Otezla. Tell your doctor about all the medicines you take, including prescription and nonprescription medicines.

Side effects of Otezla in psoriasis clinical studies were diarrhea, nausea, upper respiratory tract infection, tension headache, and headache.

Side effects of Otezla in psoriatic arthritis clinical studies were diarrhea, nausea, and headache.

These are not all the possible side effects with Otezla. Ask your doctor about other potential side effects. Tell your doctor about any side effect that bothers you or does not go away.

Tell your doctor if you are pregnant, planning to become pregnant, or planning to breastfeed. Otezla has not been studied in pregnant women or in women who are breastfeeding.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-332-1088.

Please click here for Full Prescribing Information.

Otezla® is a registered trademark of Celgene Corporation.

© 2017 Celgene Corporation 06/17
USII-APR170021

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